abstract：:Burning mouth syndrome associated to vulvodynia (Vulvostomatodynia) is a rare condition and is often difficult to diagnose and treat. Tongue, lips, vestibule and others mucosal sites may be affected by a tiresome burning sensation, especially in menopausal and postmenopausal women. Patients seldom report genital sympt...

journal_title：Maturitas

authors： Petruzzi M,De Benedittis M,Pastore L,Serpico R

更新日期：2007-09-20 00:00:00

abstract：AIM:The aim was to investigate bone mineral density (BMD) in breast cancer patients with positive estrogen receptor (ER) tumor status. METHODS:The participants were 110 postmenopausal breast cancer patients with positive estrogen receptor (ER+) tumor status. Two hundred and sixty-one age-matched, healthy postmenopausa...

journal_title：Maturitas

authors： Douchi T,Yonehara Y,Kosha S,Iwamoto I,Rai Y,Sagara Y,Umekita Y

更新日期：2007-07-20 00:00:00

abstract：OBJECTIVES:The study purpose was to evaluate the longitudinal effects, after 3 months and 1-year, of a perimenopausal health education intervention for mid-life women in Taiwan. METHODS:This study was conducted at two hospitals and their neighborhood communities (each included three subgroups, traditional Chinese, gyn...

journal_title：Maturitas

authors： Tsao LI,Su MC,Hsiao PJ,Gau YM,An C,Lin KC

更新日期：2007-07-20 00:00:00

abstract：BACKGROUND:Leydig cell tumours of the ovary are very rare benign neoplasms, frequently associated with symptoms of virilisation, in postmenopausal patients. Only four cases of bilateral Leydig tumours have been reported in the literature. CASE REPORT:We report an additional case of bilateral presentation. A 77-year-ol...

journal_title：Maturitas

authors： Sanz OA,Martinez PR,Guarch RT,Goñi MJ,Alcazar JL

更新日期：2007-06-20 00:00:00

abstract：OBJECTIVES:Levonorgestrel (LNG), delivered locally into the uterine cavity has a profound effect on the endometrium. The aim of the study was to use a LNG intrauterine system to treat non-atypical and atypical endometrial hyperplasia in women and to evaluate the long-term cure (remission) rate. METHODS:Each of the 20 ...

journal_title：Maturitas

authors： Wildemeersch D,Janssens D,Pylyser K,De Wever N,Verbeeck G,Dhont M,Tjalma W

更新日期：2007-06-20 00:00:00

abstract：OBJECTIVE:To determine whether individually tailored acupuncture is an effective treatment option for reducing postmenopausal hot flashes and improving quality of life. METHODS:In a randomized, placebo-controlled pilot study, 29 postmenopausal participants averaging at least seven moderate to severe hot flashes per 24...

journal_title：Maturitas

authors： Nir Y,Huang MI,Schnyer R,Chen B,Manber R

更新日期：2007-04-20 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate gynecologists' knowledge of the WHI study, and its repercussions on their attitudes and practice 3 years after publication. DESIGN:A self-administered, anonymous questionnaire containing 19 questions was sent to 6000 gynecologists, members of the São Paulo Society ...

journal_title：Maturitas

authors： Lazar F Jr,Costa-Paiva L,Morais SS,Pedro AO,Pinto-Neto AM

更新日期：2007-02-20 00:00:00

abstract：BACKGROUND:Quality of life decreases after the menopause as it has been assessed by several designed tools. Despite this, few studies have reported correlations between quality of life and the metabolic syndrome and its determinants. OBJECTIVE:Evaluate quality of life and determine factors related to its impairment am...

journal_title：Maturitas

authors： Chedraui P,Hidalgo L,Chavez D,Morocho N,Alvarado M,Huc A

更新日期：2007-01-20 00:00:00

abstract：OBJECTIVES:Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, of BMD by using multiple regression models in a rural Chinese population. METHODS:BMDs were measured...

journal_title：Maturitas

authors： Zalloua PA,Hsu YH,Terwedow H,Zang T,Wu D,Tang G,Li Z,Hong X,Azar ST,Wang B,Bouxsein ML,Brain J,Cummings SR,Rosen CJ,Xu X

更新日期：2007-01-20 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine the frequency with which hormone replacement therapy (HRT) was prescribed and to identify physician-related factors associated with the prescription of HRT in Spain. STUDY DESIGN:A descriptive cross-sectional survey based on a personal interview with a structured q...

journal_title：Maturitas

authors： Castelo-Branco C,Ferrer J,Palacios S,Cornago S

更新日期：2006-11-20 00:00:00

abstract：OBJECTIVE:We analysed the risk factors for clinically diagnosed uterine fibroids in women attending menopause clinics in Italy. METHODS:Between 1997 and 2003 we conducted a large cross-sectional study on the characteristics of women around menopause attending a network of first-level outpatient menopause clinics in It...

journal_title：Maturitas

authors： Parazzini F

更新日期：2006-09-20 00:00:00

abstract：OBJECTIVES:The aim of this study is to determine if the depression in perimenopausal women is symptomatologically different than depression in premenopausal women, and if these depressive women are under more risk for depression when factors like premenstrual dysphoric syndrome, socio-economical status, vasomotor sympt...

journal_title：Maturitas

authors： Oztürk O,Eraslan D,Mete HE,Ozşener S

更新日期：2006-09-20 00:00:00

abstract：OBJECTIVES:It has become popular to assert that Asian women in general have low midlife rates of reporting a wide variety of symptoms and that these rates are much lower than those found among women in western countries. Comparable data from mainland China remains sparse, however. This study aimed to uncover the sympto...

journal_title：Maturitas

authors： Shea JL

更新日期：2006-08-20 00:00:00

abstract：OBJECTIVE:Data from placebo-controlled, randomized clinical trials conducted during the past few years resulted in critical re-evaluation of the overall health benefits of hormone therapy (HT) in women during the menopausal transition and thereafter. These data stimulated vigorous debate among experts and produced seve...

journal_title：Maturitas

authors： Maia H Jr,Albernaz MA,Baracat EC,Barbosa IC,Bossemeyer R,Bueno AH,Campos OG,Carranza-Lira S,Casas PF,Castro AM,de Lima GR,de Melo NR,Fernandes CE,González JS,Larrañaga FE,Siseles N,Uribe AM,Vilchez RM,Latin American E

更新日期：2006-08-20 00:00:00

abstract：OBJECTIVES:Modern data on endometrial cancer (EC) incidence demonstrate that it is one of the most prevalent gynecologic malignancies. It is possible that some allelic polymorphisms of the genes involved in steroidogenesis or steroid metabolism differently contribute into susceptibility to described types of this disea...

journal_title：Maturitas

authors： Berstein L,Zimarina T,Imyanitov E,Kovalevskij A,Maximov S,Pujol P,Thijssen J

更新日期：2006-07-20 00:00:00

abstract：OBJECTIVE:To describe the prevalence of hormone replacement therapy (HT) use by postmenopausal women doctors and doctors' wives in Italy and to explore the relationship between their personal characteristics and HT use. DESIGN:A total of 500 women doctors and 500 men doctors answering on behalf of their female partner...

journal_title：Maturitas

authors： Biglia N,Ujcic E,Kubatzki F,Sgandurra P,Robba C,Ponzone R,Sismondi P

更新日期：2006-05-20 00:00:00

abstract：OBJECTIVE:Early onset of menopause results in the premature exposure to low estrogen levels and is associated with a number of postmenopausal health problems and higher risk of mortality. The aim of this study was to determine genetic and environmental factors associated with age at natural and surgical menopause. MET...

journal_title：Maturitas

authors： Dvornyk V,Long JR,Liu PY,Zhao LJ,Shen H,Recker RR,Deng HW

更新日期：2006-04-20 00:00:00

abstract：:Two case reports of women treated with an individual cognitive behavioral treatment (CBT) for menopausal hot flashes are presented. Both women reported substantial improvements in the number of hot flashes experienced as well as in their quality of life as measured by the Menopause Quality of Life Scale (MENQOL), the ...

journal_title：Maturitas

authors： Allen LA,Dobkin RD,Boohar EM,Woolfolk RL

更新日期：2006-04-20 00:00:00

abstract：:Combination therapy strategies for osteoporosis are reviewed in this article. Regimens including two antiresorptives agents increase BMD more than single therapy alone, but they have not proved to reduce fracture risk. The alternative of combining antiresorptives together with anabolics has gained more interest. There...

journal_title：Maturitas

authors： Garcés C,García LE

更新日期：2006-04-20 00:00:00

abstract：OBJECTIVE:To investigate the relationship between hormone replacement therapy (HRT) and level of cognitive performance intra-individual variability, and interactions with statin use, progesterone therapy and type of menopause. METHODS:A representative sample of 60-64 year olds was recruited from the Canberra and Quean...

journal_title：Maturitas

authors： Low LF,Anstey KJ,Jorm AF,Christensen H,Rodgers B

更新日期：2006-04-20 00:00:00

abstract：OBJECTIVES:Association studies between estrogen receptor alpha (ERalpha) gene polymorphisms and bone mineral density (BMD) have yielded inconsistent results. In the present study we evaluated the influence of XbaI and PvuII ERalpha gene polymorphisms on BMD, biochemical markers, rates of bone loss and the response to e...

journal_title：Maturitas

authors： Rapuri PB,Gallagher JC,Knezetic JA,Haynatzka V

更新日期：2006-03-20 00:00:00

abstract：OBJECTIVES:The objectives of the study were to find the prevalence of major depressive disorder (MDD) in male climacteric outpatients in Japan, and to determine whether symptoms on the Aging Males' Symptoms (AMS) scale scores differed between patients with and without MDD, with the aim of increasing the specificity of ...

journal_title：Maturitas

authors： Yoshida NM,Kumano H,Kuboki T

更新日期：2006-01-20 00:00:00

abstract：OBJECTIVE:To evaluate changes in mammographic density and (99m)Tc-sestamibi scintimammographic uptake in postmenopausal women on hormone replacement therapy (HRT). METHODS:Seventy-five postmenopausal women were prospectively studied and allocated into three groups: 50 women were randomized to either Group 1 (G1, n=25)...

journal_title：Maturitas

authors： Nahas-Neto J,Luca LA,Griva BL,Morceli J,Nahas EA,Moriguchi SM,Uemura G,Traiman P

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVE:To study the effects of different types of continuous hormone replacement therapy on carbohydrate metabolism. METHOD:Postmenopausal women were treated with conjugated estrogens, 0.625 mg/medroxyprogesterone acetate, 2.5 or 5 mg (CEE/MPA) or tibolone 2.5 mg daily for 13 28-day cycles. Serum glucose and insuli...

journal_title：Maturitas

authors： Odmark IS,Carlström K,Jonsson B,Jonasson AF

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVES:Pilot study to compare the effects of a continuous combined hormone replacement therapy (HRT) regimen with an interrupted progestogen regimen administered transdermally, upon the endometrium of postmenopausal women, the incidence of amenorrhoea and relief of menopausal symptoms. METHODS:Fifty-nine postmenop...

journal_title：Maturitas

authors： Cameron ST,Glasier AF,Gebbie A,Dewart H,Baird DT

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVES:To elucidate if percutanous treatment with 10mg testosterone per day could enhance sexuality and psychological well-being in postmenopausal women presenting problems with low libido. Secondary to study the influence on blood lipids, hemoglobin and erythropoietin levels. METHODS:Fifty-three postmenopausal wo...

journal_title：Maturitas

authors： Nathorst-Böös J,Flöter A,Jarkander-Rolff M,Carlström K,Schoultz Bv

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effects of different types of hormone replacement therapy (HRT) on mammographic density. MATERIALS AND METHODS:In a prospective 1-year study, 103 postmenopausal women were randomized to receive tibolone 2.5 mg/die, continuous conjugated equine estrogens 0.625 mg/die ...

journal_title：Maturitas

authors： Marchesoni D,Driul L,Ianni A,Fabiani G,Della Martina M,Zuiani C,Bazzocchi M

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVE:To describe the characteristics of women seeking treatment for symptoms of urinary incontinence (UI) in European countries. DESIGN:Prospective urinary incontinence research (PURE) was a 6-month, observational, pan-European study, primarily aimed at determining the direct costs of urinary incontinence treatme...

journal_title：Maturitas

authors： Sykes D,Castro R,Pons ME,Hampel C,Hunskaar S,Papanicolaou S,Quail D,Samsioe G,Voss S,Wagg A,Monz BU

更新日期：2005-11-30 00:00:00

abstract：OBJECTIVES:The aim of the study was to document sexual function in Kelantanese postmenopausal women. METHOD:A semi-structured questionnaire in Malay language was administered to 326 women (mean age of 57.1+/-6.58 (S.D.) years) residing in Kelantan. The subjects comprised of naturally menopaused, healthy women. RESULT...

journal_title：Maturitas

authors： Dhillon HK,Singh HJ,Ghaffar NA

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To assess the symptomatology of menopause and the use of hormone therapy among women in Spain. METHODS:A survey conducted on a representative sample of 300 women aged 45-55 in Madrid. The instrument included closed- and open-ended questions about demographic and socio-economic information, health and reprodu...

journal_title：Maturitas

authors： Obermeyer CM,Reher D,Alcala LC,Price K

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effects of two sex hormones on normal mammary gland of female rats. METHODS:Forty 250-day-old female rats, 20 of them with offspring and 20 not, were ovariectomized and, divided into 4 subgroups in order to receive one of the following subcutaneous treatment: est...

journal_title：Maturitas

authors： Pompei LM,Carvalho FM,Ortiz SC,Motta MC,Cruz RJ,Melo NR

更新日期：2005-08-16 00:00:00

abstract：OBJECTIVES:Osteoprotegerin (OPG) is a recently discovered member of the tumour necrosis factor receptor superfamily. It plays a crucial role in the control of bone resorption and its gene could therefore be a good candidate gene for osteoporosis. The aim of our work was to find polymorphisms in the OPG gene and to inve...

journal_title：Maturitas

authors： Arko B,Prezelj J,Kocijancic A,Komel R,Marc J

更新日期：2005-07-16 00:00:00

abstract：OBJECTIVE:Many observational studies suggest hormone therapy protects against coronary heart disease in contrast to findings from large randomised clinical trials and an observational Danish study. A potential bias in the observational literature concerning the cardiovascular risk and benefits associated with use of ho...

journal_title：Maturitas

authors： Løkkegaard E,Eplov LF,Køster A,Garde K

更新日期：2005-07-16 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the expression of oestrogen regulated genes in premenopausal and postmenopausal normal and malignant endometrial specimens. The molecular mechanisms and the role of these genes in endometrial carcinogenesis are poorly understood. METHODS:Normal and malignant endometrial ...

journal_title：Maturitas

authors： O'Toole SA,Dunn E,Sheppard BL,Sheils O,O'Leary JJ,Wuttke W,Seidlova-Wuttke D

更新日期：2005-06-16 00:00:00

abstract：:In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...

journal_title：Maturitas

authors： Rossouw JE

更新日期：2005-05-16 00:00:00

abstract：OBJECTIVE:We investigated, using color Doppler ultrasound, possible detectable blood changes of prolonged treatment with 17-beta-estradiol tablets on uterine artery blood flow, in a cohort of low risk postmenopausal women. METHODS:39 postmenopausal women, who were taking local estrogen therapy for at least 6 months, w...

journal_title：Maturitas

authors： Dmitrovic R,Klobucar A,Bauman R,Cvitkovic-Kuzmic A,Skalko D,Sonicki Z

更新日期：2005-04-11 00:00:00

abstract：OBJECTIVE:The present study was undertaken to assess the impact, effectiveness and safety of a monophasic hormone replacement treatment (HRT) for continuous use with regards to the clinical effects, bleeding patterns and lipid profile of menopausal women in four Latin American countries. DESIGN:Three hundred and six p...

journal_title：Maturitas

authors： Bassol S,Carranza-Lira S,Celis-Gonzalez C,Santoyo S,Murillo A,Martinez N,Santos J,Llaca V,de la Loza FR,Zarain J,da Fonseca AM,Camargos AF,Baracat EC,da Sá MF,Bayo J,Adaro L,Gurucharri C,Murga M,Siseles N,Sayegh F,

更新日期：2005-03-14 00:00:00

abstract：OBJECTIVES:The effects of supplemental testosterone on cognition, mood and wellbeing in ageing men are unclear. This study aimed to assess the effect of 12-months of oral testosterone supplementation on cognitive function, mood and quality of life in elderly men with low-normal gonadal status, not specifically selected...

journal_title：Maturitas

authors： Haren MT,Wittert GA,Chapman IM,Coates P,Morley JE

更新日期：2005-02-14 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the relationships of serum estrogen levels after hormone replacement therapy (HRT) every other day and every day with body mass index (BMI) in postmenopausal and bilaterally ovariectomized women. METHODS:Eighty-six postmenopausal and 51 bilaterally ovariectomized ...

journal_title：Maturitas

authors： Yasui T,Uemura H,Umino Y,Takikawa M,Saito S,Kuwahara A,Matsuzaki T,Maegawa M,Furumoto H,Miura M,Irahara M

更新日期：2005-01-10 00:00:00

abstract：OBJECTIVES:To evaluate the efficacy of Vitamin D for relieving vaginal atrophy. METHODS:In our cross-sectional study, 60 eligible women were consecutively identified among patients who were followed in physical medicine and rehabilitation's outpatient clinic, during the period March June 2001. The sample consisted of ...

journal_title：Maturitas

authors： Yildirim B,Kaleli B,Düzcan E,Topuz O

更新日期：2004-12-10 00:00:00